The GUCY2D Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to GUCY2D. This antibody recognizes Human antigen. The GUCY2D Antibody (Center) has been validated for the following applications: ELISA, Flow Cytometry, Immunohistochemistry, and Western Blot.
Description
This gene encodes a retina-specific guanylate cyclase,
which is a member of the membrane guanylyl cyclase family. Like
other membrane guanylyl cyclases, this enzyme has a hydrophobic
amino-terminal signal sequence followed by a large extracellular
domain, a single membrane spanning domain, a kinase homology
domain, and a guanylyl cyclase catalytic domain. In contrast to
other membrane guanylyl cyclases, this enzyme is not activated by
natriuretic peptides. Mutations in this gene result in Leber
congenital amaurosis and cone-rod dystrophy-6 diseases. [provided
by RefSeq]